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Causes

Stomach ulcers are usually caused by an infection of Helicobacter pylori (H. pylori) bacteria, or from taking anti-inflammatory medicines (NSAIDs), such as ibuprofen and aspirin.

These can break down the stomach's defence against the acid it produces to digest food, allowing the stomach lining to become damaged and an ulcer to form.

H. pylori bacteria

It’s common to have a H. pylori infection, and it’s usually harmless for most people.

But sometimes it causes ulcers in the stomach (gastric ulcer) or in the duodenum (duodenal ulcer).

It's not clear exactly why some people are more affected than others.

Anti-inflammatory medicines (NSAIDs)

NSAIDs are medicines widely used to treat pain, a high temperature (fever) and inflammation (swelling).

Commonly used NSAIDs include:

Many people take NSAIDs without having any side effects. But there's always a risk the medication could cause problems, such as stomach ulcers, particularly if taken for a long time or at high doses.

You may be advised not to take NSAIDs if you currently have or have had a stomach ulcer. 

Paracetamol can often be used as an alternative painkiller.

Lifestyle factors

There's little evidence that some lifestyle factors, like spicy foods, stress and alcohol, cause stomach ulcers. But they may make your symptoms worse.

It's thought that smoking increases your risk of developing stomach ulcers and may make treatment less effective.

Last Reviewed
21 January 2022
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Anna Sokolova
30/06/2025
I had my vaccination done there. No waiting time, and the pharmacist was very friendly. I highly recommend this place!
Matt Dooley
03/04/2025
Usually have to drop my prescription off because they don’t have it immediately so they have to order it, but they always have it by the next day. They are fast for the most part for the amount of customers they have. They are nice and courteous. I’m from the US and thought using the UK system would be a bit difficult but it’s been pretty seamless.
Renata Vincoletto
28/03/2025
Lucy Matthews
13/03/2025
Lords pharmacy always get the hard to locate medication. Pleasant team and always happy to help.
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